Benefits of Additive Noise in Composing Classes with Bounded Capacity

Many machine learning systems that are used to monitor the health and well-being of elderly individuals work based on analyzing time-series. For example, the heart  rate, location, posture, body temperature, and other signals are used during a time interval to detect a pattern. Popular approaches for learning these patterns include Recurrent Neural Networks (RNNs). But can we guarantee the performance of these machine learning models? Namely, if the model works well on a few subjects, can we argue that it will work well on the future subjects? How many training samples do we need to establish such guarantee? We developed a whole new theory to establish tighter sample complexity bounds for a variety of such models. For RNNs, our sample complexity bound depends logarithmically on the length of the input sequence while the state-of-the-art bounds were super-linear. The key idea here is to add a little bit of noise while composing layers of the architecture. Intuitively, this makes it hard for the network to “memorize”. However, noisy neural networks are now probabilistic functions and require a whole set of new tools to be analyzed. Our theory established such tools, and our experiments show that these bounds can be tighter than the best-known bounds in the literature.

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Cognition, frailty, and falls: Should they be part of fracture risk assessment?

This study aimed to investigate the association between cognition, frailty, and falls and self-reported incident fractures in community-dwelling mid- and older adults aged 45 year and older in Canada. Participants from the Canadian Longitudinal Study on Aging (CLSA) who completed the baseline assessment and the three-year follow-up questionnaires were included (n=26,982). Baseline cognitive measures, frailty index, and self-reported incident falls in the last 12 months were compared between those with and without self-reported incident fractures in the last 12 months. Multivariable logistic regression, adjusted for covariates, was used, and multicollinearity and interactions between cognition, frailty, and falls were examined. Participants who experienced incident fractures had similar cognition scores, but higher frailty index scores and greater percentage had fallen. Higher frailty index scores were associated with an increased risk of incident fractures in participants of all ages and those aged 65 or older. Falls in the past 12 months were associated with incident fractures in participants of all ages but not in those aged 65 or older. No multicollinearity and interactions between cognition, frailty, and falls were found. Given the relatively young age of the cohort, caution should be exercised when making inferences for individual older than 65 years.

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FuSeARTHRO – Functional Severity Assessments for Joint Arthroplasties

Osteoarthritis (OA) is a disease that can cause significant pain and disability, particularly in older adults. It commonly affects the knee and hip joints, leading to difficulties in daily activities, especially walking, and negatively impacting quality of life. The ultimate treatment for advanced OA is joint replacement surgery, with over 100,000 surgeries performed annually. However, little is known about how the differing functional severity of these patients, including their functional and biomechanical ability to perform general movement tasks (e.g., standing, walking, rising from a chair, stair climbing, etc.). Similarly, there is limited information on the changes in this function during the extended waiting period or following the surgery. Recent technological advancements, such as motion capture systems and wearable sensors, provide an opportunity to gather crucial information in this regard, yet limited research has directly utilized such information. Therefore, the main objective of this research project is to gather functional movement data, both in-clinic and in free-living environments, using cameras and wearable sensors. This data will be collected alongside information on pain, quality of life, and other clinical and surgical outcomes, aiming to create a more comprehensive profile of the functional severity of patients seeking joint replacement surgery for knee and hip osteoarthritis at the St. Joseph’s Healthcare Hamilton orthopaedic clinic. By doing so, this project will enhance our ability to monitor changes in functional severity and determine whether these changes are linked to surgical outcomes or treatment success. This research project aims to improve our understanding of the functional severity of patients with knee and hip osteoarthritis, both before and after joint replacement surgery, by utilizing state-of-the-art technologies such as motion capture systems and wearable sensors to collect comprehensive movement data.

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Annotating Virtual Tai Chi Instruction to Improve Learning Outcomes for Older Adults

 We conducted a focus group study in order to design and evaluate annotations that could be used to improve online Tai Chi classes. We were inspired by modern computer vision techniques including human pose estimation, human activity recognition, and object segmentation to design visual annotations that can be overlayed on an instructor’s video during live Tai Chi classes to improve participant understanding and engagement, with a particular focus on older adult Tai Chi practitioners. The focus group, which consisted of older adults with varying levels of experience with online Tai Chi classes, contributed both their feedback and their own ideas to our annotation designs. We were also joined by a Tai Chi instructor who runs online Tai Chi classes for older adults in the McMaster community; they contributed their expertise to our annotation design, and recorded the demonstration videos we used to showcase our annotations. In addition to the particular annotations we developed and evaluated, we also learned valuable guidelines that we can use to design other annotations in the future.

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Human Activity Recognition and Assessment

The use of inertial measurement unit (IMU) sensors to monitor elderly mobility status is becoming increasingly important as the global population aged 60 years or over has doubled since the 1980s. Canada is one of the countries facing the highest increase of senior population, which requires healthcare institutions to explore novel solutions to tackle this aging-related challenge. Wearable IMU sensors represent a promising solution to accurately analyze the mobility and activity of older people, which is critical for primary care providers,  such as physicians and caregivers. To that end, a team of experts in deep learning and kinesiology have proposed a comprehensive framework that combines machine learning approaches with IMU and motion capture data to estimate three-dimensional knee joint kinematics. The objective is to predict gait kinematics of healthy adults and individuals with movement disorders with high accuracy and low cost. This approach has the potential to improve the traditional and expensive kinematic estimation procedures and become more accessible for clinical patients. The researchers aim to analyze data from IMU sensors worn by elderly people to provide primary care providers with an accurate assessment of their mobility status. To overcome the data shortage limitation and improve the performance of the machine learning model, the team proposed incorporating two learning paradigms: meta-learning and multi-task learning. Moreover, the researchers plan to simulate IMU data from motion capture and video data, which has proven to be abundant and a viable alternative to conventional IMU data collection. This approach has demonstrated up to 40% improvement in accuracy compared to the baseline model on various datasets. This project has the potential to lay a foundation for a comprehensive, flexible, and low-cost biomechanical data estimation framework for assessing gait in healthy adults and people with movement disorders. This approach would enable patients and clinicians to easily monitor movement and promote health, thereby reducing the burden of musculoskeletal disorders on the national healthcare system.

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Smart Home

The Westdale Smart Home project is a revolutionary initiative aimed at helping senior citizens who are struggling to live independently. The project involves installing various sensing devices in a renovated house that monitor the movement and health of the residents. With servers located in the basement, Bluetooth relay units in every room, and real-time urine analysis in the toilet, the technology is designed to detect any anomalies in the behavior and health of the occupant, and alert caregivers or medical professionals to intervene before the situation worsens. The sensors monitor movements in the house and detect any erratic behavior that could signal impending cognitive or dementia issues. Additionally, medication usage can be monitored to ensure that it is being taken as prescribed. The Westdale Smart Home project is a bold attempt to leverage information technology, wireless communication, web-based technologies, and autonomics to develop cost-effective solutions for senior citizens’ health and wellness. The innovations developed through this project aim to help older adults lead independent lifestyles and detect early symptoms of diseases, leading to early treatment. Ultimately, the Westdale Smart Home project has the potential to revolutionize how we care for senior citizens and improve their quality of life.

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